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DZIP3 Antibody

Datasheet
Code CSB-PA080047
Size US$119
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Product Details

Uniprot No.
Q86Y13
Target Names
DZIP3
Alternative Names
DZIP3 antibody; KIAA0675E3 ubiquitin-protein ligase DZIP3 antibody; EC 2.3.2.27 antibody; DAZ-interacting protein 3 antibody; RING-type E3 ubiquitin transferase DZIP3 antibody; RNA-binding ubiquitin ligase of 138 kDa antibody; hRUL138 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human DZIP3.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Protocols
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

DZIP3 Proteins

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Target Background

Function
E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.
Gene References into Functions
  1. By monoubiquitination of H2A at lysine 119, 2A-HUB mediates a selective repression of a specific set of chemokine genes in macrophages, critically modulating migratory responses to TLR activation. PMID: 18206970
Subcellular Location
Cytoplasm.
Tissue Specificity
Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.
Database Links

HGNC: 30938

OMIM: 608672

KEGG: hsa:9666

STRING: 9606.ENSP00000355028

UniGene: Hs.409210

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  Email: [email protected]
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