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EDF1 Antibody

Datasheet
Code CSB-PA007398GA01HU
Size $600
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Product Details

Uniprot No.
O60869
Target Names
EDF1
Alternative Names
CAP19 antibody; EDF-1 antibody; edf1 antibody; EDF1_HUMAN antibody; Endothelial differentiation related factor 1 antibody; Endothelial differentiation-related factor 1 antibody; MBF1 antibody; MGC9058 antibody; Multiprotein bridging factor 1 antibody; Multiprotein-bridging factor 1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human EDF1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism.
Gene References into Functions
  1. According to this study multiprotein bridging factor 1 and Calmodulin do not interact in vitro as confirmed by NMR spectroscopy and CaM-agarose affinity chromatography. PMID: 21782027
  2. Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism. PMID: 12040021
  3. The EDF-1 minimal promoter was characterized. PMID: 16567061
Subcellular Location
Cytoplasm. Nucleus. Note=Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin.
Tissue Specificity
Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues.
Database Links

HGNC: 3164

OMIM: 605107

KEGG: hsa:8721

STRING: 9606.ENSP00000224073

UniGene: Hs.174050

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