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EXOC6 Antibody

Datasheet
Code CSB-PA007884GA01HU
Size $600
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Product Details

Uniprot No.
Q8TAG9
Target Names
EXOC6
Alternative Names
EXOC6 antibody; SEC15A antibody; SEC15L antibody; SEC15L1 antibody; Exocyst complex component 6 antibody; Exocyst complex component Sec15A antibody; SEC15-like protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human EXOC6
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
Gene References into Functions
  1. NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by triggering the switch in binding specificity of Rabin8 from PS to Sec15. PMID: 23435566
  2. coordinated disruption of the Rab11/Sec15 exocyst by anthrax toxins may contribute to toxin-dependent barrier disruption and vascular dysfunction during B. anthracis infection PMID: 20944747
  3. Sec15 has a role as an effector for the Rab11 GTPase in mammalian cells PMID: 15292201
  4. The SEC15 protein plays a crucial role in integrating the signals between Sec4p and the components of the early-polarity-establishment machinery. PMID: 16478783
Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Midbody, Midbody ring.
Protein Families
SEC15 family
Database Links

HGNC: 23196

OMIM: 609672

KEGG: hsa:54536

STRING: 9606.ENSP00000260762

UniGene: Hs.655657

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