FOXJ1 Antibody

1. Downregulation and aberrant localization of FOXJ1 may be crucial characteristics of the allergic nasal mucosa. PMID: 29635245
2. Our findings provide clues regarding the role of FOXJ1 as a tumor inducer in bladder cancer and an enhancer in glycolysis. Targeting FOXJ1 could be a potential therapeutic strategy in bladder cancer. PMID: 29129693
3. Findings demonstrate that increased FOXJ1 contributes to the progression of CRC, which might be associated with the promotion effect of b-catenin nuclear translocation. PMID: 28209947
4. In ependymomas and choroid plexus tumours, reduced expression of FOXJ1 and its ciliogenesis programme are markers of poor outcome PMID: 26690880
5. Decreased FOXJ1 expression was correlated with clinic stage, lymph node metastasis, and distant metastasis, and lower FOXJ1 expression independently predicted shorter survival time in gastric carcinoma. PMID: 24809300
6. Both protein and mRNA levels of ciliogenesis-associated markers CP110, Foxj1, TAp73 were significantly increased in patients with nasal polyps versus those seen in control subjects and were positively correlated with cilia length PMID: 25201258
7. By stimulating ciliogenesis with the transcription factor FOXJ1, it may be possible to maintain close to normal cilia length despite the stress of cigarette smoking. PMID: 24828273
8. Nanog-mediated cell migration and invasion involved its regulation of E-cadherin and FOXJ1. PMID: 22945654
9. FOXJ1 is an important regulator of cilia gene expression during ciliated cell differentiation, with RFX3 as a transcriptional co-activator to FOXJ1. PMID: 23822649
10. FOXJ1 was overexpressed in HCCs and associated with histological grade and poor prognosis. PMID: 22488567
11. Rer1p depletion reduced ciliary length and function by increasing gamma-secretase complex assembly and activity and, consequently, enhancing Notch signaling as well as reducing Foxj1a expression. PMID: 23479743
12. goblet cells formed in response to IL-13 treatment are in part or wholly derived from progenitors that express the ciliated cell marker, FOXJ1 PMID: 20539013
13. Single nucleotide polymorphisms were identified in FOXJ1 and a significant association was found with allergic rhinitis. PMID: 16518568

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HGNC: 3816

OMIM: 602291

KEGG: hsa:2302

STRING: 9606.ENSP00000323880

UniGene: Hs.651204