GALNT7 Antibody

Code CSB-PA009214GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
GALNT7
Alternative Names
GalNAc T7 antibody; GalNAc-T7 antibody; GalNAcT7 antibody; GALNT 7 antibody; Galnt7 antibody; GALT7_HUMAN antibody; N acetylgalactosaminyltransferase 7 antibody; N-acetylgalactosaminyltransferase 7 antibody; Polypeptide GalNAc transferase 7 antibody; Polypeptide N acetylgalactosaminyltransferase 7 antibody; pp GaNTase 7 antibody; pp-GaNTase 7 antibody; Protein UDP acetylgalactosaminyltransferase 7 antibody; Protein-UDP acetylgalactosaminyltransferase 7 antibody; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 7 antibody; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 7 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human GALNT7
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
Gene References into Functions
  1. miR-494 and GALNT7 play oncogenic roles in nasopharyngeal carcinoma. PMID: 26503214
  2. High expression of GALNT7 promotes migration and invasion and lymph node metastasis in esophageal squamous cell carcinoma. PMID: 27619677
  3. GALNT7 and CDK16 were confirmed to be the direct targets of miR-494. These results suggested that miR-494 play an inhibitory role in the tumorigenesis of NPC PMID: 25809707
  4. The study of miR-34a, miR-34c and its novel target, GALNT7, may serve as novel potential makers for laryngeal squamous cell carcinoma therapy. PMID: 24482044
  5. miR-214 is a new regulator of GALNT7, and both miR-214 and GALNT7 play important roles in the pathogenesis of cervical cancer PMID: 22399294
  6. Ectopic expression of miR-30b/30d promoted the metastatic behavior of melanoma cells by directly targeting the GalNAc transferase GALNT7. PMID: 21741600
  7. MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7 PMID: 19844573

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Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein Families
Glycosyltransferase 2 family, GalNAc-T subfamily
Tissue Specificity
Widely expressed. Expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS.
Database Links

HGNC: 4129

OMIM: 605005

KEGG: hsa:51809

STRING: 9606.ENSP00000265000

UniGene: Hs.548088

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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