GAREM1 Antibody

Datasheet

Code	CSB-PA863993LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA863993LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA863993LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
Citations
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GAREM1 Polyclonal antibody

Uniprot No.

Q9H706

Target Names

GAREM1

Alternative Names

GAREM1 antibody; C18orf11 antibody; FAM59A antibody; GAREM antibody; GRB2-associated and regulator of MAPK protein 1 antibody; GRB2-associated and regulator of MAPK1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human GRB2-associated and regulator of MAPK protein (12-320AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The GAREM1 Antibody (Product code: CSB-PA863993LA01HU) is Non-conjugated. For GAREM1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA863993LB01HU	GAREM1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA863993LC01HU	GAREM1 Antibody, FITC conjugated
Biotin	CSB-PA863993LD01HU	GAREM1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Citations

Icariin decreases cell proliferation and inflammation of rheumatoid arthritis-fibroblast like synoviocytes via GAREM1/MAPK signaling pathway Z Wu,Immunopharmacology and immunotoxicology,2023

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

Submit a Review here

Applications : Western blotting

Sample type: RA-FLS

Review: Western blotting examined the expression of p38, p-p38, ERK1/2, p-ERK1/2, and GAREM1 in normal FLS and RA-FLS. **P < 0.01 compared to the normal FLS group. The results were the summatory of the three replicate experiments.

By Anonymous

Target Background

Function

Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation.

Gene References into Functions

We have provided evidence that GAREM1 is involved in the PR interval of ECGs. These findings increase our understanding of the regulatory signals of heart rhythm through intracardiac ganglia of the autonomic nervous system and can be used to guide the development of a therapeutic target for heart conditions, such as atrial fibrillation. PMID: 29273731
suggest that the interplay between 14-3-3, SAM domain and CABIT domain might be responsible for the distribution of GAREM1 in mammalian cells. PMID: 26164232
Data indicate that a subtype of GAREM, GAREM2, is specifically expressed in the mouse, rat, and human brain. PMID: 24003223
Extracellular signal-regulated kinase activation in response to epidermal growth factor stimulation is regulated by the expression of GAREM in COS-7 and HeLa cells. PMID: 19509291

Protein Families

GAREM family

Tissue Specificity

Isoform 1 is ubiquitously expressed.

Database Links

HGNC: 26136

KEGG: hsa:64762

UniGene: Hs.444314

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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