GAS2L1 Antibody

Code CSB-PA859511ESR1HU
Size US$166
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  • Western blot
    All lanes: GAS2L1 antibody at 0.71µg/ml
    Lane 1: A431 whole cell lysate
    Lane 2: Hela whole cell lysate
    Lane 3: 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 73, 37, 35, 49 kDa
    Observed band size: 73, 37 kDa

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA859511ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA859511ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GAS2L1 Polyclonal antibody
Uniprot No.
Target Names
GAS2L1
Alternative Names
GA2L1_HUMAN antibody; GAR 22 antibody; GAR22 antibody; GAS2 like protein 1 antibody; GAS2 related protein on chromosome 22 antibody; GAS2-like protein 1 antibody; GAS2-related protein on chromosome 22 antibody; GAS2L1 antibody; Growth arrest specific 2 like 1 antibody; Growth arrest specific protein 2 like 1 antibody; Growth arrest-specific protein 2-like 1 antibody; MGC17243 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human GAS2-like protein 1 protein (130-400AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the cross-linking of microtubules and microfilaments. Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers.
Gene References into Functions
  1. This work reveals a GAS2L1-mediated centriole-tethering mechanism of microtubules and actin, which provide the forces required for centrosome dynamics and separation. PMID: 28017616
  2. GAS2L1 and GAS2L2 are differentially involved in mediating the crosstalk between F-actin and microtubules. PMID: 24706950
  3. There was no significant difference in the frequency six marker haplotype in the GAS2L1 gene between the cases of schizophreina and controls. PMID: 20537721
  4. The beta isoforms of hGAR17 and hGAR22 appear to be able to crosslink microtubules and microfilaments PMID: 12584248
  5. T3-induced genes identified basic transcription element binding protein 1/Kruppel-like factor 9 (BTEB1/KLF9) and GAR22 as TR target genes PMID: 19375645

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Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber.
Protein Families
GAS2 family
Database Links

HGNC: 16955

OMIM: 602128

KEGG: hsa:10634

STRING: 9606.ENSP00000344012

UniGene: Hs.322852

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