GCA Antibody

Code CSB-PA009307DSR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA009307DSR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA009307DSR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GCA Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
GCA antibody; GCL antibody; Grancalcin antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Grancalcin protein (1-217AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
Gene References into Functions
  1. Results indicate that heterodimerization of GCA and TLR9 is important for TLR9-mediated downstream signaling and might serve to fine tune processes against viral infection. PMID: 26648480
  2. GCA interacts with SRI in vivo and in vitro. PMID: 12804766
  3. The reported type 1 diabetes association is from a linkage disequilibrium region including three candidate genes, FAP, IFIH1 and GCA. PMID: 18071670
  4. IFIH1 interferon induced helicase, GCA grancalcin or the potassium channel KCNH7 - are potential candidates implicated in the pathogenesis of multiple sclerosis. PMID: 18285833
  5. IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients PMID: 19156166

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Subcellular Location
Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side.
Tissue Specificity
Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow.
Database Links

HGNC: 15990

OMIM: 607030

KEGG: hsa:25801

STRING: 9606.ENSP00000394842

UniGene: Hs.377894

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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