GCFC2 Antibody

Code CSB-PA050220
Size US$100
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Product Details

Uniprot No.
Target Names
GCFC2
Alternative Names
GCFC2 antibody; C2orf3 antibody; GCF antibody; TCF9GC-rich sequence DNA-binding factor 2 antibody; GC-rich sequence DNA-binding factor antibody; Transcription factor 9 antibody; TCF-9 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human TCF-9.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised introns.
Gene References into Functions
  1. Authors propose the GCF regulated transcriptional activity, at least in part, contributed to the upregulation of IER5 on radiation in HepG2 cells. The present findings provide insights into understanding the regulatory mechanisms of IER5. PMID: 26915404
  2. C2ORF3 protein is required for pre-mRNA splicing through its presumable role in efficient intron turnover PMID: 24304693
  3. Study refined the 2p12 candidate region in two populations and report evidence supporting MRPL19 and C2ORF3 as candidate susceptibility genes for dyslexia. PMID: 17309879
Subcellular Location
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein Families
GCF family
Tissue Specificity
Widely expressed in tissues and cell lines.
Database Links

HGNC: 1317

OMIM: 189901

KEGG: hsa:6936

STRING: 9606.ENSP00000318690

UniGene: Hs.303808

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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