GINS3 Antibody

1. The authors show that GINS is a compact tetramer in solution as observed in crystal structures, but also forms a double-tetrameric population, detectable by electron microscopy. PMID: 28071757
2. expression in primary lung adenocarcinoma plays an important role in disease progression and is a prognostic indicator PMID: 27005977
3. Psf3 expression was strongly correlated with tumor progression in non-small-cell lung cancer PMID: 26291987
4. Two downregulated genes, NDRG4 and GINS3, have been located in a genomic interval associated with cardiac repolarization in published GWASs and zebra fish knockout models PMID: 25520251
5. PSF3 expression plays an important role in the progression of colorectal cancer and acts as a factor significantly affecting the prognosis of patients. PMID: 25403684
6. a prognostic biomarker in lung adenocarcinoma PMID: 23127337
7. These results suggest that PSF3 is a potential biomarker for diagnosis of progression in colon cancer and could PMID: 20059967
8. expression of mammalian GINS is regulated by 17beta-Estradiol-stimulated estrogen receptor alpha, and PSF3 acts as a gene responsive to transcription factor E2F1 PMID: 17127213
9. This sensitized zebrafish screen identified 15 novel myocardial repolarization genes. Among these genes is GINS3, the human ortholog of which is a major locus in 2 concurrent human genome-wide association studies of QT interval. PMID: 19652097
10. This paper describes work done in Saccharomyces cerevisiae. PMID: 12730134
11. This paper describes work done in Schizosaccharomyces pombe. PMID: 16990792

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HGNC: 25851

OMIM: 610610

KEGG: hsa:64785

UniGene: Hs.47125