GMFB Antibody

Code CSB-PA006003
Size US$119
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  • Western Blot analysis of HeLa cells using GMF-β Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
GMFB
Alternative Names
Glia maturation factor beta antibody; GMF antibody; GMF-beta antibody; GMFB antibody; GMFB_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human GMF-β.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
Gene References into Functions
  1. GMF-beta is an important player in glioma progression via promoting neovascularization. PMID: 26515590
  2. The distribution of GMF-immunoreactive cells in and around amyloid plaques and neurofibrillary tangles suggests involvement of GMF in inflammatory responses through reactive glia and a role of GMF in Alzheimer disease pathology. PMID: 22035352
  3. GMF co-localizes with amyloid plaques and neurofibrillary tangles in Alzheimer brains, implicating significant upregulation of GMF expression under conditions of neurodegeneration. PMID: 21835226
  4. There is a significant increase in GMF beta protein expression levels in IFN beta-1a treated LX-2 cells. PMID: 18171522
  5. GMFB promoted T-cell differentiation into CD4-/CD8+ cells when analysed by two-colour flow cytometry. PMID: 16115230

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Protein Families
Actin-binding proteins ADF family, GMF subfamily
Database Links

HGNC: 4373

OMIM: 601713

KEGG: hsa:2764

STRING: 9606.ENSP00000350757

UniGene: Hs.151413

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