GSTM4 Antibody

Code CSB-PA009984ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA009984ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA009984ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GSTM4 Polyclonal antibody
Uniprot No.
Target Names
GSTM4
Alternative Names
Glutathione S transferase M4 antibody; Glutathione S transferase Mu 4 antibody; Glutathione S-transferase Mu 4 antibody; GST class mu 4 antibody; GST class-mu 4 antibody; GST-Mu2 antibody; GSTM4 4 antibody; GSTM4 antibody; GSTM4-4 antibody; GSTM4_HUMAN antibody; GTM4 antibody; GTS Mu2 antibody; MGC131945 antibody; MGC9247 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Glutathione S-transferase Mu 4 protein (1-218AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4. Can also catalyzes the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions.
Gene References into Functions
  1. We observed suggestive associations between survival and GSTT1 copy number and GSTA5, GSTM4, and ABCC4 single nucleotide polymorphisms PMID: 20200426
  2. A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer. PMID: 12140136
  3. a novel splice variant of GSTM4 that resulted from tandem skipping of exons 4 and 5 is identified. PMID: 16854533
  4. GSTM4 (glutathione S-transferase mu 4) haplotype 1101000 may be an important determinant for lung function growth PMID: 19151192
  5. GSTM4 contributes to the cancerous behavior of Ewing's sarcoma. PMID: 19718047

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Subcellular Location
Cytoplasm.
Protein Families
GST superfamily, Mu family
Tissue Specificity
Expressed in a wide variety of tissues.
Database Links

HGNC: 4636

OMIM: 138333

KEGG: hsa:2948

STRING: 9606.ENSP00000358851

UniGene: Hs.348387

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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