GSTM4 Antibody

Code CSB-PA009984GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
GSTM4
Alternative Names
Glutathione S transferase M4 antibody; Glutathione S transferase Mu 4 antibody; Glutathione S-transferase Mu 4 antibody; GST class mu 4 antibody; GST class-mu 4 antibody; GST-Mu2 antibody; GSTM4 4 antibody; GSTM4 antibody; GSTM4-4 antibody; GSTM4_HUMAN antibody; GTM4 antibody; GTS Mu2 antibody; MGC131945 antibody; MGC9247 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human GSTM4
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4. Can also catalyzes the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions.
Gene References into Functions
  1. We observed suggestive associations between survival and GSTT1 copy number and GSTA5, GSTM4, and ABCC4 single nucleotide polymorphisms PMID: 20200426
  2. A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer. PMID: 12140136
  3. a novel splice variant of GSTM4 that resulted from tandem skipping of exons 4 and 5 is identified. PMID: 16854533
  4. GSTM4 (glutathione S-transferase mu 4) haplotype 1101000 may be an important determinant for lung function growth PMID: 19151192
  5. GSTM4 contributes to the cancerous behavior of Ewing's sarcoma. PMID: 19718047

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Subcellular Location
Cytoplasm.
Protein Families
GST superfamily, Mu family
Tissue Specificity
Expressed in a wide variety of tissues.
Database Links

HGNC: 4636

OMIM: 138333

KEGG: hsa:2948

STRING: 9606.ENSP00000358851

UniGene: Hs.348387

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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