HAUS6 Antibody

Code CSB-PA008208GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
HAUS6
Alternative Names
HAUS6 antibody; DGT6 antibody; FAM29A antibody; KIAA1574HAUS augmin-like complex subunit 6 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human FAM29A
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin.
Gene References into Functions
  1. Hice1 and hDgt6 are core components of distinct augmin sub-complexes. PMID: 25173975
  2. Results suggest that an important mitotic function for gamma-tubulin may lie within the spindle, where augmin (Dgt2-6; FAM29A) and gamma-tubulin function cooperatively to amplify the number of microtubules. PMID: 18443220
  3. FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle. PMID: 19029337
Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein Families
HAUS6 family
Database Links

HGNC: 25948

OMIM: 613433

KEGG: hsa:54801

STRING: 9606.ENSP00000369871

UniGene: Hs.533468

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