HNRNPLL Antibody

Code CSB-PA010630LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA010630LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA010630LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HNRNPLL Polyclonal antibody
Uniprot No.
Target Names
HNRNPLL
Alternative Names
BLOCK24 antibody; Heterogeneous nuclear ribonucleoprotein L like antibody; Heterogeneous nuclear ribonucleoprotein L-like antibody; HNRLL_HUMAN antibody; hnRNPLL antibody; HNRPLL antibody; SRRF antibody; Stromal RNA regulating factor antibody; Stromal RNA-regulating factor antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Heterogeneous nuclear ribonucleoprotein L-like protein (1-72AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The HNRNPLL Antibody (Product code: CSB-PA010630LA01HU) is Non-conjugated. For HNRNPLL Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA010630LB01HU HNRNPLL Antibody, HRP conjugated ELISA
FITC CSB-PA010630LC01HU HNRNPLL Antibody, FITC conjugated
Biotin CSB-PA010630LD01HU HNRNPLL Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.
Gene References into Functions
  1. Loss-of-function mutation of hnRNPLL disrupts peripheral T cell accumulation even in the absence of CD45 protein, indicating that hnRNPLL acts through an independent mechanism to promote peripheral T cell longevity. PMID: 20505149
  2. Participation of SRRF (Stromal RNA Regulating Factor) isoforms in post-transcriptional events in bone marrow stromal cells; an important role in regulation of the RNA expression that directs the bone marrow stromal cells differentiation pathway PMID: 15256261
  3. identification of heterogeneous ribonucleoprotein L-like (hnRNPLL) as a critical inducible regulator of CD45 alternative splicing PMID: 18669861
  4. These data establish that hnRNP LL plays a critical and unique role in the signal-induced regulation of CD45 and demonstrate the utility of cell-based screens for the identification of novel splicing regulatory factors. PMID: 18719244
Tissue Specificity
Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.
Database Links

HGNC: 25127

OMIM: 611208

KEGG: hsa:92906

STRING: 9606.ENSP00000387088

UniGene: Hs.445497

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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