HOXC10 Antibody

Code CSB-PA916643
Size US$166
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  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA916643(HOXC10 Antibody) at dilution 1/225, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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Product Details

Uniprot No.
Target Names
HOXC10
Alternative Names
Hmeobox protein Hox C10 antibody; Homeobox Protein Hox C10 antibody; Homeobox protein Hox-3I antibody; Homeobox protein Hox-C10 antibody; Homeoprotein C10 antibody; Hox-3.6 antibody; HOX3I antibody; HOXC10 antibody; HXC10_HUMAN antibody; MGC5259 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human HOXC10
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Gene References into Functions
  1. Furthermore, our results showed that ectopic expression of HOXC10 could reverse inhibition of metastasis by overexpressed miR-136 in GC-9811P cells. Our findings provide new insights into the role of miR-136 in the gastric cancer-specific peritoneal metastasis and implicate the potential application of miR-136 in gastric cancer peritoneal metastasis therapy. PMID: 28656883
  2. These results indicated that HOXC10 might be a diagnostic marker for osteosarcoma and could be a potential molecular target for the therapy of osteosarcoma PMID: 28474998
  3. This study investigates the role and clinical implication of HOXC10 in human thyroid cancer. PMID: 26279264
  4. Reduced HOXC10 in vitro and in xenografts resulted in decreased apoptosis and caused antiestrogen resistance. PMID: 24670685
  5. Early mitotic dedgradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression. PMID: 12853486
  6. Cervical cancer cells with high endogenous levels of HOXC10 were less invasive after short hairpin RNA-mediated knockdown of HOXC10 expression; findings support a key role for the HOXC10 homeobox protein in cervical cancer progression PMID: 17974957
  7. Data demonstrate that HOXC10 is a gene that may discriminate between amnion-derived mesenchymal stem cells (MSCs) and decidua-derived MSCs. PMID: 19522674

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Subcellular Location
Nucleus.
Protein Families
Abd-B homeobox family
Database Links

HGNC: 5122

OMIM: 605560

KEGG: hsa:3226

STRING: 9606.ENSP00000307321

UniGene: Hs.44276

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