HSD17B14 Antibody

Code CSB-PA010771GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
HSD17B14
Alternative Names
HSD17B14 antibody; DHRS10 antibody; SDR3 antibody; SDR47C1 antibody; UNQ502/PRO47417-beta-hydroxysteroid dehydrogenase 14 antibody; 17-beta-HSD 14 antibody; EC 1.1.1.- antibody; 17-beta-hydroxysteroid dehydrogenase DHRS10 antibody; Dehydrogenase/reductase SDR family member 10 antibody; Retinal short-chain dehydrogenase/reductase retSDR3 antibody; Short chain dehydrogenase/reductase family 47C member 1 antibody
Species Reactivity
Human,Mouse,Rat
Immunogen
Human HSD17B14
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).
Gene References into Functions
  1. Results show that tumoural expression levels of 17betaHSD14 can predict the outcome of adjuvant tamoxifen treatment in terms of local recurrence-free survival in patients with lymph node-negative ER+ breast cancer. PMID: 22792371
  2. crystal structure of the DHRS10 apoenzyme exhibits secondary structure of the SDR (short-chain dehydrogenase/reductase) family PMID: 17067289
Subcellular Location
Cytoplasm.
Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Tissue Specificity
Highly expressed in brain, placenta, liver and kidney.
Database Links

HGNC: 23238

OMIM: 612832

KEGG: hsa:51171

STRING: 9606.ENSP00000263278

UniGene: Hs.18788

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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