HSD17B14 Antibody

Code CSB-PA859026HA01HU
Size US$166
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  • Western blot
    All lanes: HSD17B14 antibody at 2µg/ml + Mouse kidney tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 29 kDa
    Observed band size: 29 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HSD17B14 Polyclonal antibody
Uniprot No.
Target Names
HSD17B14
Alternative Names
HSD17B14 antibody; DHRS10 antibody; SDR3 antibody; SDR47C1 antibody; UNQ502/PRO47417-beta-hydroxysteroid dehydrogenase 14 antibody; 17-beta-HSD 14 antibody; EC 1.1.1.- antibody; 17-beta-hydroxysteroid dehydrogenase DHRS10 antibody; Dehydrogenase/reductase SDR family member 10 antibody; Retinal short-chain dehydrogenase/reductase retSDR3 antibody; Short chain dehydrogenase/reductase family 47C member 1 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human 17-beta-hydroxysteroid dehydrogenase 14 protein (1-270AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The HSD17B14 Antibody (Product code: CSB-PA859026HA01HU) is Non-conjugated. For HSD17B14 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA859026HB01HU HSD17B14 Antibody, HRP conjugated ELISA
FITC CSB-PA859026HC01HU HSD17B14 Antibody, FITC conjugated
Biotin CSB-PA859026HD01HU HSD17B14 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).
Gene References into Functions
  1. Results show that tumoural expression levels of 17betaHSD14 can predict the outcome of adjuvant tamoxifen treatment in terms of local recurrence-free survival in patients with lymph node-negative ER+ breast cancer. PMID: 22792371
  2. crystal structure of the DHRS10 apoenzyme exhibits secondary structure of the SDR (short-chain dehydrogenase/reductase) family PMID: 17067289
Subcellular Location
Cytoplasm.
Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Tissue Specificity
Highly expressed in brain, placenta, liver and kidney.
Database Links

HGNC: 23238

OMIM: 612832

KEGG: hsa:51171

STRING: 9606.ENSP00000263278

UniGene: Hs.18788

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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