ICAM5 Antibody

Code CSB-PA892475ESR2HU
Size US$166
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  • Western blot
    All lanes: ICAM5 antibody at 4.2μg/ml
    Lane 1: HepG2 whole cell lysate
    Lane 2: A549 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 97 kDa
    Observed band size: 97 kDa

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA892475ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ICAM5 Polyclonal antibody
Uniprot No.
Target Names
ICAM5
Alternative Names
ICAM5 antibody; TLCN antibody; TLNIntercellular adhesion molecule 5 antibody; ICAM-5 antibody; Telencephalin antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Intercellular adhesion molecule 5 protein (32-180AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
Gene References into Functions
  1. Here the authors identify neuron-specific intercellular adhesion molecule 5 (ICAM-5/telencephalin) as a cellular receptor for sialic acid-dependent and -independent entry of enterovirus D68. PMID: 27923705
  2. ICAM5 V301I and rs281439 variants may contribute to the susceptibility of breast cancer. [Meta-analysis] PMID: 23079714
  3. A specific microenvironment facilitating ARF6-mediated mobilization of TLN that contributes to promotion of dendritic spine development. PMID: 22781129
  4. study does not confirm association between ICAM 5 V3001 polymorphism and breast cancer risk PMID: 16434609
  5. ICAM-5 is involved in immune privilege of the brain and acts as an anti-inflammatory agent. PMID: 18223167

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Subcellular Location
Membrane; Single-pass type I membrane protein.
Protein Families
Immunoglobulin superfamily, ICAM family
Tissue Specificity
Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
Database Links

HGNC: 5348

OMIM: 601852

KEGG: hsa:7087

STRING: 9606.ENSP00000221980

UniGene: Hs.465862

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