IDI2 Antibody

Code CSB-PA010995GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
IDI2
Alternative Names
IDI2 antibody; Isopentenyl-diphosphate delta-isomerase 2 antibody; EC 5.3.3.2 antibody; Isopentenyl pyrophosphate isomerase 2 antibody; IPP isomerase 2 antibody; IPPI2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human IDI2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
Gene References into Functions
  1. The present findings suggest that IDI1 and IDI2 may be associated with the production of cholesterol metabolites in neurons, leading to alpha-synuclein aggregation during the process of Lewy body formation. PMID: 25950736
  2. Within the 40-kb region on 10p15.3 subtelomere, which harbours two genes encoding isopentenyl diphosphate isomerase 1 (IDI1) and IDI2, there was found a segmental copy-number gain in a large proportion of sporadic amyotrophic lateral sclerosis patients. PMID: 20955688
  3. IDI2 is expressed at high levels only in skeletal muscle, where it may be involved in the specialized production of isoprenyl diphosphates for the posttranslational modification of proteins. PMID: 14629038
  4. Enzyme kinetic analysis; both isozymes IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway; data suggest that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPARalpha PMID: 17202134
Subcellular Location
Peroxisome.
Protein Families
IPP isomerase type 1 family
Tissue Specificity
Muscle-specific expression.
Database Links

HGNC: 23487

OMIM: 615389

KEGG: hsa:91734

STRING: 9606.ENSP00000277517

UniGene: Hs.591325

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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