ITGB1BP2 Antibody

Code CSB-PA011882GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ITGB1BP2
Alternative Names
ITGB1BP2 antibody; MSTP015 antibody; Integrin beta-1-binding protein 2 antibody; Melusin antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ITGB1BP2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a role during maturation and/or organization of muscles cells.
Gene References into Functions
  1. Studies in mouse show that melusin prevents cardiac dilation during chronic pressure overload by specifically sensing mechanical stress. PMID: 12496958
  2. Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy PMID: 23124043
  3. The altered melusin pathways and CDC42 parallel the cardiac function progression during cardiac remodeling post-MI. PMID: 21546274
  4. Our analysis revealed an extremely low number of variations in the ITGB1BP2 gene in nearly 1000 hypertensive/cardiopathic and healthy individuals, thus suggesting a high degree of conservation of the melusin gene within the populations analyzed PMID: 20017903
Tissue Specificity
Expressed in skeletal and cardiac muscles but not in other tissues.
Database Links

HGNC: 6154

OMIM: 300332

KEGG: hsa:26548

STRING: 9606.ENSP00000362935

UniGene: Hs.109999

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