JMY Antibody, HRP conjugated

1. In autophagosomes, the integrity of the WH2 domains allows JMY to promote actin nucleation, which is required for efficient autophagosome formation. PMID: 26223951
2. JMY was expressed in normal tissues and heterogeneously in different tumor types, with close correlation between cytoplasmic and nuclear expression. PMID: 25280461
3. JARID1A, JMY, and PTGER4 polymorphisms are related to ankylosing spondylitis in Chinese Han patients. PMID: 24069348
4. JMY is related to the severity of AS in Chinese Han patients. PMID: 23758122
5. actin assembly regulates nuclear import of JMY in response to DNA damage. PMID: 22262458
6. JMY is expressed at high levels in brain tissue, and in various cell lines JMY is predominantly cytoplasmic, with a minor fraction in the nucleus. PMID: 21965285
7. results establish the interplay between JMY and HIF-1alpha as a new mechanism that controls cell motility under hypoxic stress PMID: 21625218
8. Data demonstrate a pathway that links the cytoskeleton with the p53 response, and further suggest that the ability of JMY to regulate actin and cadherin is instrumental in coordinating cell motility with the p53 response. PMID: 19897726
9. JMY represents a new class of multifunctional actin assembly factor whose activity is regulated, at least in part, by sequestration in the nucleus. PMID: 19287377

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HGNC: 28916

OMIM: 604279

KEGG: hsa:133746

STRING: 9606.ENSP00000379441

UniGene: Hs.482605