KCNC4 Antibody

1. This study provides original evidence to demonstrate the early occurrence and high prevalence of abnormal Kv3.4 expression in oral leucoplakias. Our results support a role for Kv3.4 potassium channel in OSCC tumorigenesis rather than tumour progression and disease outcome. PMID: 26648458
2. These results suggest a novel peripheral mechanism of post-spinal cord injury pain sensitization implicating Kv3.4 channel dysregulation and potential Kv3.4-based therapeutic interventions. PMID: 25609640
3. Ionizing radiation-induced G2/M arrest was preceded by activation of Kv3.4-like voltage-gated potassium channels. PMID: 23443853
4. these data suggest that Kv3.4 and Cav1.2 may act together to control Ca(2) -dependent electrical activity of pioneer axons and play important roles during axon pathfinding. PMID: 22473424
5. Kv3.4 channels exert a permissive role in the cell cycle progression of proliferating uterine vascular smooth cells. PMID: 20093253
6. Kv3.4 was overexpressed in early stages of Alzheimer disease and in advanced stages was present at high levels in neurodegenerative structures. This subunit regulates delayed-rectifier currents, primary determinants of spike repolarization in neurones PMID: 15485486
7. The characterization of a missense mutation in MiRP2 that affects its phosphorylation and consequent interactions with Kv3.4 is reported. PMID: 16449802

Show More

Hide All

HGNC: 6236

OMIM: 176265

KEGG: hsa:3749

STRING: 9606.ENSP00000358802

UniGene: Hs.153521