KCNG3 Antibody

Code CSB-PA703878
Size US$119
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  • Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using Kv10.1 Rabbit pAb diluted at 1:200.
  • Immunohistochemical analysis of paraffin-embedded Mouse BrainTissue using Kv10.1 Rabbit pAb diluted at 1:200.
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Product Details

Uniprot No.
Target Names
KCNG3
Alternative Names
KCNG3; Potassium voltage-gated channel subfamily G member 3; Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic Peptide
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IHC,ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; this promotes a reduction in the rate of activation and inactivation of the delayed rectifier voltage-gated potassium channel KCNB1.
Gene References into Functions
  1. the correlation between dismal prognosis and Kv10.1 expression to patients with brain metastases or glioblastoma multiforme and, moreover, they strongly suggest a role of tricyclic antidepressants for personalized therapy of brain malignancies. PMID: 26530050
  2. [review] an overview of the current status of data linking K(V)10.1 to cancer, and techniques that could exploit K(V)10.1's properties for the management of cancer PMID: 22204340
  3. These results indicate that Kv6.3 is a novel member of the voltage-gated K(+) channel which functions as a modulatory subunit of the Kv2.1 channel. PMID: 11852086
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cytoplasm.
Protein Families
Potassium channel family, G (TC 1.A.1.2) subfamily, Kv6.3/KCNG3 sub-subfamily
Tissue Specificity
Expressed in the brain, liver, testis, small intestine, colon, thymus and adrenal gland.
Database Links

HGNC: 18306

OMIM: 606767

KEGG: hsa:170850

STRING: 9606.ENSP00000304127

UniGene: Hs.352633

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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