KCNH7 Antibody

Code CSB-PA012041GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
KCNH7
Alternative Names
KCNH7 antibody; ERG3Potassium voltage-gated channel subfamily H member 7 antibody; Ether-a-go-go-related gene potassium channel 3 antibody; ERG-3 antibody; Eag-related protein 3 antibody; Ether-a-go-go-related protein 3 antibody; hERG-3 antibody; Voltage-gated potassium channel subunit Kv11.3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human KCNH7
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly.
Gene References into Functions
  1. we have discovered that, the Kv11.3 (hERG3) a plasma-membrane potassium channel plays a critical role in the regulation of autophagy in a melanoma cell model PMID: 26942884
  2. KCNH7 c.1181G>A had the highest enrichment among individuals with bipolar spectrum disorder (x2 5 7.3) and the strongest family-based association with bipolar 1 (P 5 0.021), bipolar spectrum (P 5 0.031) and any major affective disorder (P 5 0.016). PMID: 24986916
  3. The recombinant wild-type ERG3 protein produced in HEK cells generates two prominent bands. When the entire CNBD of ERG3 protein was deleted, only an EndoH-sensitive band was generated, indicating that this band constitutes the immature species. PMID: 15961404
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.3/KCNH7 sub-subfamily
Tissue Specificity
Expressed in prolactin-secreting adenomas.
Database Links

HGNC: 18863

OMIM: 608169

KEGG: hsa:90134

STRING: 9606.ENSP00000331727

UniGene: Hs.657413

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