KYAT1 Antibody

Datasheet

Code	CSB-PA613699LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA613699LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA613699LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KYAT1 Polyclonal antibody

Uniprot No.

Q16773

Target Names

KYAT1

Alternative Names

KYAT1 antibody; CCBL1 antibody; Kynurenine--oxoglutarate transaminase 1 antibody; EC 2.6.1.7 antibody; Cysteine-S-conjugate beta-lyase antibody; EC 4.4.1.13 antibody; Glutamine transaminase K antibody; GTK antibody; Glutamine--phenylpyruvate transaminase antibody; EC 2.6.1.64 antibody; Kynurenine aminotransferase 1 antibody; Kynurenine aminotransferase I antibody; KATI antibody; Kynurenine--oxoglutarate transaminase I antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Kynurenine--oxoglutarate transaminase 1 protein (1-372AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The KYAT1 Antibody (Product code: CSB-PA613699LA01HU) is Non-conjugated. For KYAT1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA613699LB01HU	KYAT1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA613699LC01HU	KYAT1 Antibody, FITC conjugated
Biotin	CSB-PA613699LD01HU	KYAT1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.

Gene References into Functions

Immunohistochemical analysis revealed the presence of KAT I, II, and III in all examined corneal sections. PMID: 28706436
CH(3)Hg-S-Cys and Cys-S-Hg-S-Cys are substrates and reversible inhibitors of GTK. PMID: 22093698
major biological roles of glutamine transaminase K are to maintain low levels of phenylpyruvate and to close the methionine salvage pathway--REVIEW PMID: 15016471
We found elevated cerebellar KAT-1 activities in post-mortem brain samples from schizophrenic versus normal individuals. PMID: 16828464
alpha-keto acids generated by transamination/l-amino acid oxidase activity of the two catechol cysteine S-conjugates are unstable PMID: 18342615

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Subcellular Location

Cytoplasm, cytosol.

Protein Families

Class-I pyridoxal-phosphate-dependent aminotransferase family

Database Links

HGNC: 1564

OMIM: 600547

KEGG: hsa:883

STRING: 9606.ENSP00000302227

UniGene: Hs.495250

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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