CCBL1 Antibody

Code CSB-PA004616GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
KYAT1
Alternative Names
KYAT1 antibody; CCBL1 antibody; Kynurenine--oxoglutarate transaminase 1 antibody; EC 2.6.1.7 antibody; Cysteine-S-conjugate beta-lyase antibody; EC 4.4.1.13 antibody; Glutamine transaminase K antibody; GTK antibody; Glutamine--phenylpyruvate transaminase antibody; EC 2.6.1.64 antibody; Kynurenine aminotransferase 1 antibody; Kynurenine aminotransferase I antibody; KATI antibody; Kynurenine--oxoglutarate transaminase I antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CCBL1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. Also metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.
Gene References into Functions
  1. Immunohistochemical analysis revealed the presence of KAT I, II, and III in all examined corneal sections. PMID: 28706436
  2. CH(3)Hg-S-Cys and Cys-S-Hg-S-Cys are substrates and reversible inhibitors of GTK. PMID: 22093698
  3. major biological roles of glutamine transaminase K are to maintain low levels of phenylpyruvate and to close the methionine salvage pathway--REVIEW PMID: 15016471
  4. We found elevated cerebellar KAT-1 activities in post-mortem brain samples from schizophrenic versus normal individuals. PMID: 16828464
  5. alpha-keto acids generated by transamination/l-amino acid oxidase activity of the two catechol cysteine S-conjugates are unstable PMID: 18342615

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Subcellular Location
Cytoplasm, cytosol.
Protein Families
Class-I pyridoxal-phosphate-dependent aminotransferase family
Database Links

HGNC: 1564

OMIM: 600547

KEGG: hsa:883

STRING: 9606.ENSP00000302227

UniGene: Hs.495250

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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