L3MBTL3 Antibody

Code CSB-PA012712GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
L3MBTL3
Alternative Names
L3MBTL3 antibody; H-l(3)mbt-like protein 3 antibody; Hl(3)mbt like protein antibody; KIAA1798 antibody; l(3)mbt like 3 (Drosophila) antibody; l(3)mbt like 3 antibody; L(3)mbt like 3 protein antibody; L(3)mbt-like protein 3 antibody; L3mbtl3 antibody; Lethal(3)malignant brain tumor like 3 protein antibody; Lethal(3)malignant brain tumor-like protein 3 antibody; LMBL3_HUMAN antibody; MBT-1 antibody; MBT1 antibody; RP11-73O6.1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Human L3MBTL3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells.
Gene References into Functions
  1. RBPJ interacts with L3MBTL3 to promote repression of Notch signaling via histone demethylase KDM1A. PMID: 29030483
  2. Mutation in L3MBTL3 gene is associated with insulin-resistant cardiometabolic disease. PMID: 27841877
  3. The mouse MBT-1 protein influences myelopoiesis by transiently enhancing p57(KIP2) expression levels. PMID: 15889154
Subcellular Location
Nucleus.
Database Links

HGNC: 23035

KEGG: hsa:84456

STRING: 9606.ENSP00000354526

UniGene: Hs.658051

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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