LAIR2 Antibody

Code CSB-PA313669
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA313669(LAIR2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA313669(LAIR2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
LAIR2
Alternative Names
CD306 antibody; CD306 antigen antibody; LAIR 2 antibody; LAIR-2 antibody; LAIR2 antibody; LAIR2_HUMAN antibody; Leukocyte associated Ig like receptor 2 antibody; Leukocyte associated immunoglobulin like receptor 2 antibody; Leukocyte-associated immunoglobulin-like receptor 2 antibody; MGC71634 antibody; OTTHUMP00000068389 antibody; OTTHUMP00000068390 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human LAIR2
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions
  1. recombinant LAIR-2-Fc inhibits complement-mediated lysis of cells sensitized with anti-HLA antibodies PMID: 24192271
  2. the presence of high LAIR-2 levels in 74/80 sera from patients with autoimmune thyroid diseases PMID: 23691008
  3. LAIR2-expressing extravillous trophoblasts associate with maternal spiral arterioles undergoing physiologic conversion PMID: 23332415
  4. Two markers in two different genes (CNOT3 and LAIR2) showed significant association with ankylosing spondylitis. PMID: 22294640
  5. LAIR-2/Fc has the capacity to interfere with platelet-collagen interactions mediated by Glycoprotein VI and the VWF/Glycoprotein Ib axis. PMID: 20730098
  6. Human collagen II peptides II-17, -27, -30, -35, -38, -42, -49 & -56; and collagen III peptides III-1, 5, -8, -10, -12, -13, -22, -30, -38, -40, -44, -45, and -51 specifically interacted with hLAIR-2 expressed on K562 cells PMID: 19345263

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Subcellular Location
Secreted.
Database Links

HGNC: 6478

OMIM: 602993

KEGG: hsa:3904

STRING: 9606.ENSP00000301202

UniGene: Hs.43803

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