LAIR2 Antibody

Code CSB-PA016594
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA016594(LAIR2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA016594(LAIR2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Raw264.7, 231 cells, Raji cells, Primary antibody: CSB-PA016594(LAIR2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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Product Details

Uniprot No.
Target Names
LAIR2
Alternative Names
CD306 antibody; CD306 antigen antibody; LAIR 2 antibody; LAIR-2 antibody; LAIR2 antibody; LAIR2_HUMAN antibody; Leukocyte associated Ig like receptor 2 antibody; Leukocyte associated immunoglobulin like receptor 2 antibody; Leukocyte-associated immunoglobulin-like receptor 2 antibody; MGC71634 antibody; OTTHUMP00000068389 antibody; OTTHUMP00000068390 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human LAIR2
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. recombinant LAIR-2-Fc inhibits complement-mediated lysis of cells sensitized with anti-HLA antibodies PMID: 24192271
  2. the presence of high LAIR-2 levels in 74/80 sera from patients with autoimmune thyroid diseases PMID: 23691008
  3. LAIR2-expressing extravillous trophoblasts associate with maternal spiral arterioles undergoing physiologic conversion PMID: 23332415
  4. Two markers in two different genes (CNOT3 and LAIR2) showed significant association with ankylosing spondylitis. PMID: 22294640
  5. LAIR-2/Fc has the capacity to interfere with platelet-collagen interactions mediated by Glycoprotein VI and the VWF/Glycoprotein Ib axis. PMID: 20730098
  6. Human collagen II peptides II-17, -27, -30, -35, -38, -42, -49 & -56; and collagen III peptides III-1, 5, -8, -10, -12, -13, -22, -30, -38, -40, -44, -45, and -51 specifically interacted with hLAIR-2 expressed on K562 cells PMID: 19345263

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Subcellular Location
Secreted.
Database Links

HGNC: 6478

OMIM: 602993

KEGG: hsa:3904

STRING: 9606.ENSP00000301202

UniGene: Hs.43803

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