LRR1 Antibody

Code CSB-PA836247LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA836247LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA836247LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA836247LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LRR1 Polyclonal antibody
Uniprot No.
Target Names
LRR1
Alternative Names
4 1BB mediated signaling molecule antibody; 4 1BBlrr antibody; 4-1BB-mediated-signaling molecule antibody; 4-1BBlrr antibody; Cyclophilin like 5 antibody; Leucine-rich repeat protein 1 antibody; LLR1_HUMAN antibody; LRR 1 antibody; LRR repeat protein 1 antibody; LRR-1 antibody; LRR-repeat protein 1 antibody; LRR1 antibody; MGC20689 antibody; peptidylprolyl isomerase (cyclophilin) like 5 antibody; Peptidylprolyl isomerase like 5 antibody; Peptidylprolyl isomerase-like 5 antibody; PPIL5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Leucine-rich repeat protein 1 protein (18-159AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LRR1 Antibody (Product code: CSB-PA836247LA01HU) is Non-conjugated. For LRR1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA836247LB01HU LRR1 Antibody, HRP conjugated ELISA
FITC CSB-PA836247LC01HU LRR1 Antibody, FITC conjugated
Biotin CSB-PA836247LD01HU LRR1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Gene References into Functions
  1. Results identify the CRL2(LRR-1) ubiquitin ligase as a conserved regulator of Cip/Kip CKIs that promotes the degradation of C. elegans CKI-1 and human p21. PMID: 21074724
Tissue Specificity
Ubiquitous. Maximal expression was seen in the heart and skeletal muscle and minimal expression seen in the kidney.
Database Links

HGNC: 19742

OMIM: 609193

KEGG: hsa:122769

STRING: 9606.ENSP00000298288

UniGene: Hs.451090

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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