LSM1 Antibody

Code CSB-PA013199LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA013199LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA013199LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LSM1 Polyclonal antibody
Uniprot No.
Target Names
LSM1
Alternative Names
Cancer associated Sm like protein antibody; Cancer associated Sm-like antibody; Cancer-associated Sm-like antibody; CASM antibody; lsm1 antibody; LSM1 antibody antibody; LSM1 homolog; U6 small nuclear RNA associated (S. cerevisiae) antibody; Lsm1 protein antibody; LSM1; U6 small nuclear RNA associated antibody; LSM1_HUMAN antibody; Small nuclear ribonuclear CaSm antibody; U6 snRNA associated Sm-like protein LSm1 antibody; U6 snRNA-associated Sm-like protein LSm1 antibody; YJL124C antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human U6 snRNA-associated Sm-like protein LSm1 protein (1-133AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LSM1 Antibody (Product code: CSB-PA013199LA01HU) is Non-conjugated. For LSM1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA013199LB01HU LSM1 Antibody, HRP conjugated ELISA
FITC CSB-PA013199LC01HU LSM1 Antibody, FITC conjugated
Biotin CSB-PA013199LD01HU LSM1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.
Gene References into Functions
  1. These results provide evidence that LSm1 binding to the DENV RNA 3' UTR positively regulates DENV RNA replication. PMID: 25872476
  2. The results of this study provided further support for previous genetic findings reporting the association of an intronic SNP (rs16887244) in LSM1 and schizophrenia in a Chinese sample PMID: 24035562
  3. Lsm1 is deeply involved in prostate cancer progression through its down-regulation, independent of any gene mutation. PMID: 11953827
  4. LSM1 is a breast cancer oncogene from the 8p11-12 amplicon. PMID: 17001308
  5. Results suggest that LSm-1/CaSm functions as an oncogene in the promotion of cellular transformation and cancer progression. PMID: 18218995

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Subcellular Location
Cytoplasm. Cytoplasm, P-body.
Protein Families
SnRNP Sm proteins family
Database Links

HGNC: 20472

OMIM: 607281

KEGG: hsa:27257

STRING: 9606.ENSP00000310596

UniGene: Hs.425311

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