LYPLA2 Antibody

Code CSB-PA05074A0Rb
Size US$166
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  • Immunofluorescent analysis of Hela cells using CSB-PA05074A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LYPLA2 Polyclonal antibody
Uniprot No.
Target Names
LYPLA2
Alternative Names
Acyl protein thioesterase 2 antibody; Acyl protein thioesterase antibody; Acyl-protein thioesterase 2 antibody; APT 2 antibody; APT-2 antibody; APT2 antibody; DJ886K2.4 antibody; EC 3.1.2.- antibody; LPL I antibody; LPL II antibody; LPL-II antibody; LYPA2_HUMAN antibody; LYPLA 2 antibody; Lypla2 antibody; Lysophospholipase II antibody; LysoPLA II antibody; OTTHUMP00000002999 antibody; OTTHUMP00000044831 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Acyl-protein thioesterase 2 protein (1-226AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LYPLA2 Antibody (Product code: CSB-PA05074A0Rb) is Non-conjugated. For LYPLA2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA05074B0Rb LYPLA2 Antibody, HRP conjugated ELISA
FITC CSB-PA05074C0Rb LYPLA2 Antibody, FITC conjugated
Biotin CSB-PA05074D0Rb LYPLA2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide.
Gene References into Functions
  1. LYPLA2 is the major prostaglandin glycerol ester hydrolase in human cancer cells. PMID: 25301951
  2. Results demonstrate that APT-2 is the protein thioesterase involved in the acylation/deacylation cycle operating in GAP-43 subcellular distribution. PMID: 21152083
Subcellular Location
Cytoplasm.
Protein Families
AB hydrolase superfamily, AB hydrolase 2 family
Tissue Specificity
Expressed in various breast cancer cell lines.
Database Links

HGNC: 6738

KEGG: hsa:11313

STRING: 9606.ENSP00000363638

UniGene: Hs.533479

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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