LYPLA2 Antibody

Datasheet

Code	CSB-PA05074A0Rb
Size	US$166
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Image	Immunofluorescent analysis of Hela cells using CSB-PA05074A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) LYPLA2 Polyclonal antibody

Uniprot No.

O95372

Target Names

LYPLA2

Alternative Names

Acyl protein thioesterase 2 antibody; Acyl protein thioesterase antibody; Acyl-protein thioesterase 2 antibody; APT 2 antibody; APT-2 antibody; APT2 antibody; DJ886K2.4 antibody; EC 3.1.2.- antibody; LPL I antibody; LPL II antibody; LPL-II antibody; LYPA2_HUMAN antibody; LYPLA 2 antibody; Lypla2 antibody; Lysophospholipase II antibody; LysoPLA II antibody; OTTHUMP00000002999 antibody; OTTHUMP00000044831 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Acyl-protein thioesterase 2 protein (1-226AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The LYPLA2 Antibody (Product code: CSB-PA05074A0Rb) is Non-conjugated. For LYPLA2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA05074B0Rb	LYPLA2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA05074C0Rb	LYPLA2 Antibody, FITC conjugated
Biotin	CSB-PA05074D0Rb	LYPLA2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide.

Gene References into Functions

LYPLA2 is the major prostaglandin glycerol ester hydrolase in human cancer cells. PMID: 25301951
Results demonstrate that APT-2 is the protein thioesterase involved in the acylation/deacylation cycle operating in GAP-43 subcellular distribution. PMID: 21152083

Subcellular Location

Cytoplasm.

Protein Families

AB hydrolase superfamily, AB hydrolase 2 family

Tissue Specificity

Expressed in various breast cancer cell lines.

Database Links

HGNC: 6738

KEGG: hsa:11313

STRING: 9606.ENSP00000363638

UniGene: Hs.533479

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Email: [email protected]
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Antibody Service

Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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