LYPLA2 Antibody

Code CSB-PA05074A0Rb
Size US$166
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  • Immunofluorescent analysis of Hela cells using CSB-PA05074A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LYPLA2 Polyclonal antibody
Uniprot No.
Target Names
LYPLA2
Alternative Names
Acyl protein thioesterase 2 antibody; Acyl protein thioesterase antibody; Acyl-protein thioesterase 2 antibody; APT 2 antibody; APT-2 antibody; APT2 antibody; DJ886K2.4 antibody; EC 3.1.2.- antibody; LPL I antibody; LPL II antibody; LPL-II antibody; LYPA2_HUMAN antibody; LYPLA 2 antibody; Lypla2 antibody; Lysophospholipase II antibody; LysoPLA II antibody; OTTHUMP00000002999 antibody; OTTHUMP00000044831 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Acyl-protein thioesterase 2 protein (1-226AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LYPLA2 Antibody (Product code: CSB-PA05074A0Rb) is Non-conjugated. For LYPLA2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA05074B0Rb LYPLA2 Antibody, HRP conjugated ELISA
FITC CSB-PA05074C0Rb LYPLA2 Antibody, FITC conjugated
Biotin CSB-PA05074D0Rb LYPLA2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide.
Gene References into Functions
  1. LYPLA2 is the major prostaglandin glycerol ester hydrolase in human cancer cells. PMID: 25301951
  2. Results demonstrate that APT-2 is the protein thioesterase involved in the acylation/deacylation cycle operating in GAP-43 subcellular distribution. PMID: 21152083
Subcellular Location
Cytoplasm.
Protein Families
AB hydrolase superfamily, AB hydrolase 2 family
Tissue Specificity
Expressed in various breast cancer cell lines.
Database Links

HGNC: 6738

KEGG: hsa:11313

STRING: 9606.ENSP00000363638

UniGene: Hs.533479

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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