MESP1 Antibody

Datasheet

Code	CSB-PA871559ESR2HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA871559ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA871559ESR2HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MESP1 Polyclonal antibody

Uniprot No.

Q9BRJ9

Target Names

MESP1

Alternative Names

bHLHc5 antibody; Class C basic helix-loop-helix protein 5 antibody; Mesoderm posterior 1 antibody; Mesoderm posterior 1 homolog (mouse) antibody; Mesoderm posterior 1 homolog antibody; Mesoderm posterior protein 1 antibody; MESP 1 antibody; Mesp1 antibody; MESP1_HUMAN antibody; MGC10676 antibody; MGC159208 antibody; MGC159210 antibody; OTTMUSP00000030151 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Mesoderm posterior protein 1 protein (149-268AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.

Gene References into Functions

The present study firstly provided experimental evidence supporting the concept that a MESP1 lossoffunction mutation may contribute to the development of double outlet right ventricle in humans, which presents a significant insight into the molecular pathogenesis of congenital heart disease. PMID: 28677747
results suggest that pathologic variants in MESP1 may contribute to the development of congenital heart disease (CHD) and that additional protein partners and downstream targets could likewise contribute to the wide range of causes for CHD PMID: 26694203
The MESP1-NKX2-5 hESC reporter line allows us to identify molecular cues crucial for specification and expansion of human cardiac mesoderm and early progenitors and their differentiation to specific cardiovascular derivatives. PMID: 25187301
MESP1 SNPs are associated with congenital heart disease in patients and altered transcription in vitro. PMID: 24056064
Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors. PMID: 22826236
MesP1 drives vertebrate cardiovascular differentiation through Dkk-1-mediated blockade of Wnt-signalling PMID: 18297060

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Subcellular Location

Nucleus.

Database Links

HGNC: 29658

OMIM: 608689

KEGG: hsa:55897

STRING: 9606.ENSP00000300057

UniGene: Hs.447531

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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