METTL21A Antibody

Code CSB-PA008022GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
METTL21A
Alternative Names
F119A_HUMAN antibody; FAM119A antibody; Family with sequence similarity 119 member A antibody; HCA557b antibody; Hepatocellular carcinoma-associated antigen 557b antibody; Hypothetical protein LOC151194 antibody; LOC151194 antibody; Methyltransferase like 21A antibody; Methyltransferase like protein 21A antibody; METTL21A antibody; MGC45373 antibody; Protein FAM119A antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human FAM119A
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8.
Gene References into Functions
  1. methyltransferase METTL21A is the enzyme responsible for trimethylation of a conserved lysine residue found in several human Hsp70 (HSPA) proteins PMID: 23921388
  2. METTL21A trimethylates Lys-561 in Hsp70 and corresponding residues in other isoforms (Hsc70, BiP) PMID: 23349634
Subcellular Location
Cytoplasm.
Protein Families
Methyltransferase superfamily, METTL21 family
Database Links

HGNC: 30476

OMIM: 615257

KEGG: hsa:151194

STRING: 9606.ENSP00000385481

UniGene: Hs.664764

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