MOCS1 Antibody

Datasheet

Code	CSB-PA878934ESR2HU
Size	US$166
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Image	Western blot All lanes: MOCS1 antibody at 2.24 μg/ml + Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 71, 44, 41, 32, 69, 59 kDa Observed band size: 71, 55 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MOCS1 Polyclonal antibody

Uniprot No.

Q9NZB8

Target Names

MOCS1

Alternative Names

Cell migration-inducing gene 11 protein antibody; MIG11 antibody; Migration inducing gene 11 protein antibody; MOCOD antibody; MOCODA antibody; Mocs1 antibody; MOCS1_HUMAN antibody; Molybdenum cofactor biosynthesis protein 1 antibody; Molybdenum cofactor biosynthesis protein A antibody; Molybdenum cofactor biosynthesis protein C antibody; Molybdenum cofactor synthesis 1 antibody; Molybdenum cofactor synthesis-step 1 protein A-B antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Molybdenum cofactor biosynthesis protein 1 protein (90-360AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cPMP.

Gene References into Functions

Case Report: in a mild case of molybdenum cofactor deficiency detected two proteins: a truncated MOCS1AB protein and a 22.4 kDa protein representing MOCS1B, demonstrating an unusual mechanism of translation re-initiation in the MOCS1 transcript, which results in trace amounts of functional MOCS1B protein being sufficient to partially protect the patient from the most severe symptoms. PMID: 29368224
Review: A total of 32 different disease-causing mutations, including several common to more than one family, have been identified in molybdenum cofactor-deficient patients and their relatives PMID: 12754701
MOCS1A is an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesis PMID: 15180982
genetic and protein structural analysis of MOCS1 in molybdenum cofactor deficiency [case report] PMID: 17065069

Involvement in disease

Molybdenum cofactor deficiency, complementation group A (MOCODA)

Protein Families

MoaC family; Radical SAM superfamily, MoaA family

Tissue Specificity

Isoform MOCS1A and isoform 2 are widely expressed.

Database Links

HGNC: 7190

OMIM: 252150

KEGG: hsa:4337

STRING: 9606.ENSP00000362282

UniGene: Hs.357128

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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