MSC Antibody

Datasheet

Code	CSB-PA015025LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human lymph node tissue using CSB-PA015025LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA015025LA01HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MSC Polyclonal antibody

Uniprot No.

O60682

Target Names

MSC

Alternative Names

ABF-1 antibody; ABF1 antibody; Activated B cell factor 1 antibody; Activated B-cell factor 1 antibody; bHLHa22 antibody; Class A basic helix-loop-helix protein 22 antibody; Msc antibody; MUSC_HUMAN antibody; Musculin antibody; MYOR antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Musculin protein (3-143AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The MSC Antibody (Product code: CSB-PA015025LA01HU) is Non-conjugated. For MSC Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA015025LB01HU	MSC Antibody, HRP conjugated	ELISA
FITC	CSB-PA015025LC01HU	MSC Antibody, FITC conjugated
Biotin	CSB-PA015025LD01HU	MSC Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.

Gene References into Functions

this study shows that musculin inhibits human T-helper 17 cell response to interleukin 2 by controlling STAT5B activity PMID: 28612433
results demonstrate that ABF-1 facilitates formation of memory B cells but prevents plasma cell differentiation. PMID: 25070843
role in repressing lymphotoxin alpha PMID: 15052269
ABF-1 is frequently silenced by promoter methylation in follicular lymphoma, diffuse large B-cell lymphoma and Burkitt's lymphoma. PMID: 18368067

Subcellular Location

Nucleus.

Tissue Specificity

Expressed in lymphoid tissues, B-cell lines and activated B-cells.

Database Links

HGNC: 7321

OMIM: 603628

KEGG: hsa:9242

STRING: 9606.ENSP00000321445

UniGene: Hs.442619

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Email: [email protected]
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Service

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Protein Service

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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