MT-ND2 Antibody

1. gene variants not associated with total fertilization failure PMID: 29577757
2. The C5263T single-nucleotide mutation of the mitochondrial ND2 gene was observed in 2 young coronary heart disease (CHD) patients in the case group. The premature CHD of these 2 patients followed a pattern of maternal inheritance. PMID: 28494837
3. Data show no association between the mitochondrial 5178C/A polymorphism of NADH-dehydrogenase subunit 2 (ND2) gene with type-2 diabetes mellitus (T2DM), however, the polymorphism may affect the development of nephropathy and hypertension complications. PMID: 26663065
4. Study identified cancer-specific somatic variants in the ND2 and ND3 regions, and the presence of these mutated DNAs in the serum during the postoperative period accurately predicted poor prognoses in oral squamous cell carcinomas. PMID: 26179426
5. This study did not show a correlation between ARMS2, C3, MT-NDH2, and CFH alleles in the development of choroid neovascularization associated with ocular histoplasmosis. PMID: 24612979
6. The Mt5178 C/A genotype, which results in an amino acid polymorphism in NADH dehydrogenase subunit 2, may modify longitudinal changes in serum total cholesterol and high-density lipoprotein cholesterol levels in middle-aged Japanese men. PMID: 22351520
7. demethylation of the D-loop plays a key role in regulating ND2 expression during the initiation and/or progression of colorectal cancer. PMID: 22505229
8. For Mt5178C genotypic men, alcohol consumption may reduce the risk of hyper-LDL cholesterolemia PMID: 21702983
9. Mutation T4681C disturbs the mitochondrial electron transport complex I assembly pathway and leads to Leigh syndrome. PMID: 16996290
10. results suggest that ND2-237 Leu/Met polymorphism is associated with hypertension and that modification of hypertension risk is dependent on alcohol consumption in middle-aged Japanese men PMID: 17510502
11. mitochondrial MTND2 polymorphism may increase susceptibility to nucleoside reverse transcriptase inhibitors associated peripheral neuropathy PMID: 17684475
12. modifies the effects of coffee consumption on blood pressure or the risk of hypertension PMID: 19667492

Show More

Hide All

HGNC: 7456

OMIM: 502500

KEGG: hsa:4536

STRING: 9606.ENSP00000355046