MYBL1 Antibody

Code CSB-PA015263ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA015263ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA015263ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MYBL1 Polyclonal antibody
Uniprot No.
Target Names
MYBL1
Alternative Names
A-Myb antibody; AMYB antibody; MGC120059 antibody; MGC120061 antibody; Myb related protein A antibody; Myb-like protein 1 antibody; Myb-related protein A antibody; MYBA_HUMAN antibody; MYBL1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Myb-related protein A protein (503-752AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Transcriptional activator of SOX30.
Gene References into Functions
  1. Low MYBL1 expression is associated with colon cancer. PMID: 28096468
  2. Our study defines new molecular subclasses of ACC characterized by MYBL1 rearrangements and 5'-NFIB gene fusions. PMID: 26631609
  3. Thus, the LIMD1-MYBL1 Index had considerable clinical value for DLBCL subtype classification and prognosis. PMID: 25940947
  4. analysis of genetic alterations in MYBL1 in diffuse pediatric low-grade gliomas PMID: 23633565
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.
Database Links

HGNC: 7547

OMIM: 159405

KEGG: hsa:4603

STRING: 9606.ENSP00000429633

UniGene: Hs.445898

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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