MYH1 Antibody

1. Transcriptional levels of MHC-I, MHC-IIa, and MHC-IIb in denervation groups were significantly down-regulated compared with controls PMID: 26059207
2. Myosin isoforms impact single-fiber force generation and may lead to alterations in whole skeletal muscle performance. PMID: 25567808
3. adaptive response to reduced masticatory load was lower numerical and area proportion of MyHC-1 expressing fibres and higher numerical proportion of hybrid fibres in edentulous compared with dentate subjects PMID: 22489880
4. The human genioglossus muscle is composed of conventional myosin heavy chain isoforms and 3 primary myosin heavy chain phenotypes. PMID: 22337492
5. the expression levels of the MHC genes are associated with age and both PGC-1alpha and PGC-1beta and indicate that the MHC genes may to some extent be used to determine fibre-type composition in human skeletal muscle. PMID: 21470888
6. we found a higher percentage of fibers expressing fast MyHC IIx in tetraplegic cerebral palsy PMID: 17916367
7. Modular organization of phylogenetically conserved domains controlling developmental regulation of the human skeletal gene family PMID: 11971910
8. frequency of fibers expressing myosin heavy chain (MyHC) IIx increased in spastic paresis PMID: 17196619
9. Patients on hemodialysis demonstrate relatively fewer type 1 and consequently more type 2x fibres, with a corresponding change in MHC isoforms (MHC I and MHC IIX) in the skeletal muscle. PMID: 17853024

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HGNC: 7567

OMIM: 160730

KEGG: hsa:4619

STRING: 9606.ENSP00000226207

UniGene: Hs.689619