MYO16 Antibody

Code CSB-PA008306
Size US$100
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Product Details

Uniprot No.
Target Names
MYO16
Alternative Names
MYO16 antibody; KIAA0865 antibody; MYO16B antibody; NYAP3 antibody; Unconventional myosin-XVI antibody; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3 antibody; Unconventional myosin-16 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human Myosin XVI.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis.
Gene References into Functions
  1. KIRREL3 interacting proteins MAP1B and MYO16 are potential candidates for intellectual disability and autism spectrum disorder. PMID: 25902260
  2. This study suggest that common variation within MYO16 may contribute to the genetic liability to schizophrenia. PMID: 24141571
Subcellular Location
Cytoplasm.
Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Myosin family; NYAP family
Database Links

HGNC: 29822

OMIM: 615479

KEGG: hsa:23026

STRING: 9606.ENSP00000349145

UniGene: Hs.656587

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