NFRKB Antibody

Code CSB-PA003423
Size US$100
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  • Western Blot analysis of COS7 cells using NFRκB Polyclonal Antibody
  • Western Blot analysis of various cells using NFRκB Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
NFRKB
Alternative Names
NFRKB antibody; INO80G antibody; Nuclear factor related to kappa-B-binding protein antibody; DNA-binding protein R kappa-B antibody; INO80 complex subunit G antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Monkey
Immunogen
Synthesized peptide derived from the Internal region of Human NFRκB.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex.
Gene References into Functions
  1. Data show that DEUBAD domain in RPN13 (ADRM1) activates ubiquitin thioesterase L5 (UCH-L5), and the related DEUBAD domain in INO80G (NFRKB) inhibits UCH-L5. PMID: 25702870
  2. The structure of a novel helical domain of NFRKB was determined to 2.18 A resolution. PMID: 22984442
  3. NFRKB may be involved in the disorders of transcriptional regulation commonly observed in minimal change nephrotic syndrome relapse. PMID: 22291976
Subcellular Location
Nucleus.
Protein Families
NFRKB family
Tissue Specificity
Expressed in thymus, brain, testes, spleen and liver.
Database Links

HGNC: 7802

OMIM: 164013

KEGG: hsa:4798

STRING: 9606.ENSP00000436926

UniGene: Hs.530539

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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