NPFF Antibody

Code CSB-PA015981ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA015981ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA015981ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NPFF Polyclonal antibody
Uniprot No.
Target Names
NPFF
Alternative Names
NPFF antibody; Pro-FMRFamide-related neuropeptide FF antibody; FMRFamide-related peptides) [Cleaved into: Neuropeptide SF antibody; NPSF); Neuropeptide FF antibody; NPFF); Neuropeptide AF antibody; NPAF)] antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Pro-FMRFamide-related neuropeptide FF protein (34-113AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels.
Gene References into Functions
  1. Our results...highlight the neuropeptide FF-amide peptide encoding gene (NPFF) as a novel candidate risk gene for both migraine with aura and migraine without aura PMID: 26660531
  2. reduction of NPFF release within the dorsal motor nucleus and ambiguus nucleus could serve as a possible cause of the impairment of cardiac vagal control in hypertensive patients PMID: 21120930
  3. expression of hNPFF2 receptor mRNA was up-regulated by neuropeptide FF PMID: 16336216
  4. neuropeptide FF and micro-opioid receptor association could be a possible molecular basis for anti-opioid activity PMID: 17224450
  5. the findings from the early studies on the analgesic and morphine modulating activities suggested a role for NPFF in pain modulation--review PMID: 17854890

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Subcellular Location
Secreted.
Protein Families
FARP (FMRFamide related peptide) family
Database Links

HGNC: 7901

OMIM: 604643

KEGG: hsa:8620

STRING: 9606.ENSP00000267017

UniGene: Hs.733076

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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