NSUN7 Antibody

Code CSB-PA822769LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA822769LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA822769LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NSUN7 Polyclonal antibody
Uniprot No.
Target Names
NSUN7
Alternative Names
NSUN7Putative methyltransferase NSUN7 antibody; EC 2.1.1.- antibody; NOL1/NOP2/Sun domain family member 7 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Putative methyltransferase NSUN7 protein (1-300AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The NSUN7 Antibody (Product code: CSB-PA822769LA01HU) is Non-conjugated. For NSUN7 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA822769LB01HU NSUN7 Antibody, HRP conjugated ELISA
FITC CSB-PA822769LC01HU NSUN7 Antibody, FITC conjugated
Biotin CSB-PA822769LD01HU NSUN7 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May have S-adenosyl-L-methionine-dependent methyl-transferase activity.
Gene References into Functions
  1. mutant protein structures of Nsun7 indicated that the amino acid serine was converted to alanine, the structure of the helix, coil and strand was changed, and the protein folding and ligand binding sites were changed in samples from asthenospermic men with a transversion mutation in exon 7, indicating impairment of protein function. Because Nsun7 plays a role in sperm motility, mutation in exon 7 may lead to infertility. PMID: 24384068
  2. Our findings revealed that genetic polymorphisms in exon7 of the NSUN7 gene are not associated with asthenospermia in Chinese Han men. PMID: 26345859
  3. Nsun7 (A11337)-deletion mutation, causes reduction of its protein rate and associated with sperm motility defect in infertile men. PMID: 25702163
Protein Families
Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
Database Links

HGNC: 25857

KEGG: hsa:79730

STRING: 9606.ENSP00000371201

UniGene: Hs.479602

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