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OCIAD1 Antibody

Datasheet
Code CSB-PA016259GA01HU
Size $600
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Product Details

Uniprot No.
Q9NX40
Target Names
OCIAD1
Alternative Names
Asrij antibody; FLJ20455 antibody; MGC111072 antibody; OCAD1_HUMAN antibody; OCIA antibody; OCIA domain containing 1 antibody; OCIA domain-containing protein 1 antibody; OCIAD1 antibody; Ovarian carcinoma immunoreactive antigen antibody; TPA018 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human OCIAD1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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OCIAD1 Proteins

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Target Background

Function
Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes. Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer.
Gene References into Functions
  1. Like OCIAD1, OCIAD2 is a cancer-related protein and its expression level increases during the course of malignant progression and is thought to be a very useful marker for evaluating the malignancy of ovarian mucinous tumors. PMID: 22726067
  2. OCIAD1 is a potential biomarker of thyroid carcinoma but had no significant additive effect on the risk of distant metastasis. PMID: 22081784
  3. This is the first study to indicate that OCIAD1 is a key player in generating ovarian cancer recurrence. PMID: 20515946
  4. Over-expressed in metastatic ovarian cancer. Effect of OCIAD1 on cell adhesion may be related to its function in ovarian cancer. Possibility of OCIAD1's role in tumor metastasis. PMID: 18328549
Subcellular Location
Endosome.
Protein Families
OCIAD1 family
Tissue Specificity
Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord.
Database Links

HGNC: 16074

KEGG: hsa:54940

STRING: 9606.ENSP00000264312

UniGene: Hs.518750

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