PABPC4 Antibody

Code CSB-PA017357GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PABPC4
Alternative Names
Activated platelet protein 1 antibody; Activated-platelet protein 1 antibody; APP 1 antibody; APP-1 antibody; APP1 antibody; FLJ43938 antibody; Inducible poly(A) binding protein antibody; Inducible poly(A)-binding protein antibody; iPABP antibody; IPABP4 antibody; PABP 4 antibody; PABP-4 antibody; PABP4 antibody; PABP4_HUMAN antibody; PABPC 4 antibody; PABPC4 antibody; Poly A binding protein cytoplasmic 4 antibody; Poly(A) binding protein 4 antibody; Poly(A) binding protein cytoplasmic 4 (inducible form) antibody; Poly(A) binding protein cytoplasmic 4 antibody; Poly(A)-binding protein 4 antibody; Polyadenylate binding protein 4 antibody; Polyadenylate-binding protein 4 antibody; Polyadenylate-binding protein; cytoplasmic; 4 antibody; Polyadenylate-binding protein; inducible antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PABPC4
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.
Gene References into Functions
  1. The PABPC4 rs4660293 SNP is associated with serum lipid levels. PMID: 26005159
  2. PABPC4 is highly expressed in human colorectal cancer. PMID: 22884093
  3. Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export PMID: 21940797
  4. RNA binding masks nuclear import signals within the cytoplasmic poly(A) binding protein RNA recognition motifs, thereby ensuring ef fi cient cytoplasmic retention of this protein in normal cells PMID: 21646427
Subcellular Location
Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein Families
Polyadenylate-binding protein type-1 family
Tissue Specificity
Expressed at low levels in resting normal T cells; following T-cell activation, however, mRNA levels are rapidly up-regulated.
Database Links

HGNC: 8557

OMIM: 603407

KEGG: hsa:8761

STRING: 9606.ENSP00000361949

UniGene: Hs.169900

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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