PCF11 Antibody

Datasheet

Code	CSB-PA017603LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA017603LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA017603LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PCF11 Polyclonal antibody

Uniprot No.

O94913

Target Names

PCF11

Alternative Names

hPCF11 antibody; KIAA0824 antibody; OTTHUMP00000234826 antibody; PCF11 antibody; PCF11 cleavage and polyadenylation factor subunit antibody; PCF11; cleavage and polyadenylation factor II subunit; homolog antibody; PCF11; cleavage and polyadenylation factor subunit; homolog (S. antibody; PCF11_HUMAN antibody; PCF11p homolog antibody; Pre-mRNA cleavage complex 2 protein Pcf11 antibody; Pre-mRNA cleavage complex II protein Pcf11 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Pre-mRNA cleavage complex 2 protein Pcf11 protein (409-604AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PCF11 Antibody (Product code: CSB-PA017603LA01HU) is Non-conjugated. For PCF11 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA017603LB01HU	PCF11 Antibody, HRP conjugated	ELISA
FITC	CSB-PA017603LC01HU	PCF11 Antibody, FITC conjugated
Biotin	CSB-PA017603LD01HU	PCF11 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of pre-mRNA cleavage complex II.

Gene References into Functions

WNK1 and the associated phosphorylation of the PCF11 CID act to promote transcript release from chromatin-associated Pol II, which in turn facilitates mRNA export to the cytoplasm PMID: 29196535
Pcf11 can act as a negative elongation factor to repress RNA Pol II gene expression in eukaryotic cells. PMID: 17606639
Pcf11 is required for the efficient degradation of the 3' product of poly(A) site cleavage. PMID: 18086705
Human PCf11 is a pre-mRNA processing factor. PMID: 11060040

Subcellular Location

Nucleus.

Database Links

HGNC: 30097

OMIM: 608876

KEGG: hsa:51585

STRING: 9606.ENSP00000298281

UniGene: Hs.128959

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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