PCID2 Antibody

Datasheet

Code	CSB-PA705514LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA705514LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA705514LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PCID2 Polyclonal antibody

Uniprot No.

Q5JVF3

Target Names

PCID2

Alternative Names

CSN12 like protein antibody; CSN12-like protein antibody; DKFZp686C20226 antibody; F10 antibody; FLJ11305 antibody; FLJ99362 antibody; HT004 antibody; MGC16774 antibody; PCI domain containing 2 antibody; PCI domain containing protein 2 antibody; PCI domain-containing protein 2 antibody; PCID2 antibody; PCID2_HUMAN antibody; RP11 - 98F14.6 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human PCI domain-containing protein 2 protein (2-250AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PCID2 Antibody (Product code: CSB-PA705514LA01HU) is Non-conjugated. For PCID2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA705514LB01HU	PCID2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA705514LC01HU	PCID2 Antibody, FITC conjugated
Biotin	CSB-PA705514LD01HU	PCID2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (Probable). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells.

Gene References into Functions

Data show that PCI domain-containing protein 2 (Pcid2) controls lymphoid lineage commitment through the regulation of Snf2-related CREBBP activator protein (SRCAP) remodelling activity. PMID: 29138493
Pcid2 is present in the CBP/p300-EID1 complex to control the switch balance of mouse and human embryonic stem cells through modulation of EID1 degradation. PMID: 24167073
First discovery of specific novel functions for PCID2 other than mRNA export and components of the TREX-2 complex serve alternative shared roles in the regulation of nuclear transport and cell cycle progression. PMID: 24291146
validated occurrence of an unusual TG 3' splice site in intron 2 PMID: 17672918

Subcellular Location

Cytoplasm. Nucleus, nuclear pore complex.

Protein Families

CSN12 family

Database Links

HGNC: 25653

OMIM: 613713

KEGG: hsa:55795

STRING: 9606.ENSP00000337405

UniGene: Hs.508769

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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