PDP2 Antibody

Code CSB-PA868395LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PDP2 Polyclonal antibody
Uniprot No.
Target Names
PDP2
Alternative Names
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2 antibody; KIAA1348 antibody; mitochondrial antibody; PDP 2 antibody; Pdp2 antibody; PDP2_HUMAN antibody; PDPC 2 antibody; PPM2B antibody; PPM2C2 antibody; Protein phosphatase 2C magnesium dependent catalytic subunit 2 antibody; Protein phosphatase Mg2+/Mn2+ dependent 2B antibody; Pyruvate dehydrogenase phosphatase 2 antibody; Pyruvate dehydrogenase phosphatase catalytic subunit 2 antibody; pyruvate dehydrogenase phosphatase isoenzyme 2 antibody; Pyruvate dehydrogenase phosphatase; catalytic subunit 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial protein (67-529AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PDP2 Antibody (Product code: CSB-PA868395LA01HU) is Non-conjugated. For PDP2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA868395LB01HU PDP2 Antibody, HRP conjugated ELISA
FITC CSB-PA868395LC01HU PDP2 Antibody, FITC conjugated
Biotin CSB-PA868395LD01HU PDP2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
Gene References into Functions
  1. ICER was found to bind to the Pdp2 promoter and suppress its expression. Furthermore, forced expression of PDP2 in CD4(+) cells reduced the in vitro Th17 differentiation, whereas shRNA-based suppression of PDP2 expression increased in vitro Th17 differentiation PMID: 30150402
  2. catalytic subunit of PDP2 crystals belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 53.6, b = 69.1, c = 109.7 A. PMID: 20208177
Subcellular Location
Mitochondrion matrix.
Protein Families
PP2C family
Database Links

HGNC: 30263

OMIM: 615499

KEGG: hsa:57546

STRING: 9606.ENSP00000309548

UniGene: Hs.632214

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