PDP2 Antibody

Code CSB-PA004699
Size US$100
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  • Western Blot analysis of K562 cells using PDP2 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
PDP2
Alternative Names
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2 antibody; KIAA1348 antibody; mitochondrial antibody; PDP 2 antibody; Pdp2 antibody; PDP2_HUMAN antibody; PDPC 2 antibody; PPM2B antibody; PPM2C2 antibody; Protein phosphatase 2C magnesium dependent catalytic subunit 2 antibody; Protein phosphatase Mg2+/Mn2+ dependent 2B antibody; Pyruvate dehydrogenase phosphatase 2 antibody; Pyruvate dehydrogenase phosphatase catalytic subunit 2 antibody; pyruvate dehydrogenase phosphatase isoenzyme 2 antibody; Pyruvate dehydrogenase phosphatase; catalytic subunit 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human PDP2.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
Gene References into Functions
  1. ICER was found to bind to the Pdp2 promoter and suppress its expression. Furthermore, forced expression of PDP2 in CD4(+) cells reduced the in vitro Th17 differentiation, whereas shRNA-based suppression of PDP2 expression increased in vitro Th17 differentiation PMID: 30150402
  2. catalytic subunit of PDP2 crystals belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 53.6, b = 69.1, c = 109.7 A. PMID: 20208177
Subcellular Location
Mitochondrion matrix.
Protein Families
PP2C family
Database Links

HGNC: 30263

OMIM: 615499

KEGG: hsa:57546

STRING: 9606.ENSP00000309548

UniGene: Hs.632214

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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