PDP2 Antibody

Datasheet

Code	CSB-PA004699
Size	US$119
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Image	Western Blot analysis of K562 cells using PDP2 Polyclonal Antibody
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9P2J9

Target Names

PDP2

Alternative Names

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2 antibody; KIAA1348 antibody; mitochondrial antibody; PDP 2 antibody; Pdp2 antibody; PDP2_HUMAN antibody; PDPC 2 antibody; PPM2B antibody; PPM2C2 antibody; Protein phosphatase 2C magnesium dependent catalytic subunit 2 antibody; Protein phosphatase Mg2+/Mn2+ dependent 2B antibody; Pyruvate dehydrogenase phosphatase 2 antibody; Pyruvate dehydrogenase phosphatase catalytic subunit 2 antibody; pyruvate dehydrogenase phosphatase isoenzyme 2 antibody; Pyruvate dehydrogenase phosphatase; catalytic subunit 2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human PDP2.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:20000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.

Gene References into Functions

ICER was found to bind to the Pdp2 promoter and suppress its expression. Furthermore, forced expression of PDP2 in CD4(+) cells reduced the in vitro Th17 differentiation, whereas shRNA-based suppression of PDP2 expression increased in vitro Th17 differentiation PMID: 30150402
catalytic subunit of PDP2 crystals belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 53.6, b = 69.1, c = 109.7 A. PMID: 20208177

Subcellular Location

Mitochondrion matrix.

Protein Families

PP2C family

Database Links

HGNC: 30263

OMIM: 615499

KEGG: hsa:57546

STRING: 9606.ENSP00000309548

UniGene: Hs.632214

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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